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The concept of column switching is shown
below. Glutamate (red) is eluting over a 5 + 15 cm column in
series. When glutamate is on the second column, a valve
switches thus
bypassing the second column for GABA (blue).
Also other late eluting peaks will not enter column 2, thus
conveniently avoiding chromatographic problems in the
following runs.
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ALEXYS System Solutions
The
DECADE II has a column switch option installed, to minimise
run time and maximise resolution. Column switching is used for example in
ALEXYS GABA/Glu.
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