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Antec Leyden has developed integrated system solutions for the analysis
of noradrenaline, dopamine, serotonin and metabolites in microdialysates. Microdialysis
systems are optimised for analysis of small sample volumes at picomolar
detection limits.
Table 1. Microdialysis System Solutions
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Part no. |
Description |
| 180.0072 |
Nitrotyrosine
- DCC |
|
180.0068 |
Disulfides I - DCC for RED-OX of
(di-)glutathione, cysteine, homocysteine |
| 180.0064 |
Microdialysis III
- DCC using OX-RED mode |
Read more about systems for disulfides
or nitrotyrosine. These systems use the
same configuration.
For the analysis of microdialysates we selected the VT03 electrochemical
cell. This cell not only has an excellent reproducibility but also the
best possible detection sensitivity. A reactor cell is used for
oxidation prior to reductive detection. We use a 1 mm ID column at
50 µL/min.
The ALEXYS system comprises the following parts:
- AS 100 autosampler, cool, micro
- LC 110 HPLC pump
- OR 110 organiser rack
- Clarity data acquisition software
- DECADE II electrochemical detector, DCC
- VT cell with GC WE, ISAAC
- Reactor cell
- 213-018 - Dual cell control
for improved selectivity
- 221-006 - Ox-Red analysis
for selectivity improvement using the DECADE II with Dual Cell Control
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ALEXYS
'Microdialysis III'
with 150 x 1 mm column, reactor and VT
cell. The DECADE II has dual cell control (DCC).
Other microdialysis configurations are available.
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